Muscle Mass Loss With GLP-1 Therapy: Clinical Relevance and Mitigation
glp1 · Lancet Diabetes & Endocrinology · 2025
~25–40% of weight lost on GLP-1 is lean mass — enough to push older adults toward sarcopenia without protein + resistance training.
Authors
Prado CM, Phillips SM, Gonzalez MC, Heymsfield SB
Research lens
~25–40% of weight lost on GLP-1 is lean mass — enough to push older adults toward sarcopenia without protein + resistance training.
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