A randomised controlled trial of dietary improvement for adults with major depression (the SMILES trial)

nutrition · BMC Medicine · 2017

The first RCT to show that diet alone — Mediterranean pattern, real food — can produce remission in major depression. Nutrition is not adjunctive to mental health. It is structural.

Authors

Jacka FN, O'Neil A, Opie R, Itsiopoulos C, Cotton S, Mohebbi M, Castle D, Dash S, Mihalopoulos C, Chatterton ML, Brazionis L, Dean OM, Hodge AM, Berk M

Research lens

The first RCT to show that diet alone — Mediterranean pattern, real food — can produce remission in major depression. Nutrition is not adjunctive to mental health. It is structural.

  • nutrition
  • depression
  • mediterranean
  • mental health