Probiotics and synbiotics modestly reduce depression and anxiety

gut-brain · Examine.com Study Summaries — June 8–15, 2026 · 2026

Meta-analysis of 70 RCTs (5,770 participants): probiotics and synbiotics produced modest but real reductions in depression and anxiety symptoms vs. placebo.

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Examine.com

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Meta-analysis of 70 RCTs (5,770 participants): probiotics and synbiotics produced modest but real reductions in depression and anxiety symptoms vs. placebo.

  • probiotics
  • synbiotics
  • depression
  • anxiety
  • gut-brain axis