Effect of Continued vs Withdrawn Semaglutide on Weight Maintenance (STEP 4)

glp1 · JAMA · 2021

Stopping semaglutide after 20 weeks caused patients to regain 6.9% body weight over the next 48 weeks; those who continued lost another 7.9%.

Authors

Rubino D, Abrahamsson N, Davies M, et al.

Research lens

Stopping semaglutide after 20 weeks caused patients to regain 6.9% body weight over the next 48 weeks; those who continued lost another 7.9%.

  • glp1
  • weight-regain
  • discontinuation
  • maintenance