Burnout and the brain: a mechanistic review of MRI studies

Burnout neurobiology · International Journal of Molecular Sciences · 2025

17 studies, ~1,365 people: burnout shows amygdala enlargement, prefrontal grey-matter loss and weaker amygdala–ACC coupling, with the hippocampus spared.

Authors

Chmiel, Kurpas

Research lens

17 studies, ~1,365 people: burnout shows amygdala enlargement, prefrontal grey-matter loss and weaker amygdala–ACC coupling, with the hippocampus spared.

  • burnout
  • amygdala
  • prefrontal
  • new-2026-10